Cargando…

The role of plasminogen activator inhibitor-2 in pneumococcal meningitis

Pneumococcal meningitis is associated with dysregulation of the coagulation cascade. Previously, we detected upregulation of cerebral plasminogen activator inhibitor-2 (PAI-2) mRNA expression during pneumococcal meningitis. Diverse functions have been ascribed to PAI-2, but its role remains unclear....

Descripción completa

Detalles Bibliográficos
Autores principales:	Teske, Nina C., Engelen-Lee, Joo-Yeon, Dyckhoff-Shen, Susanne, Pfister, Hans-Walter, Klein, Matthias, van de Beek, Diederik, Kirschning, Carsten K., Koedel, Uwe, Brouwer, Matthijs C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617400/ https://www.ncbi.nlm.nih.gov/pubmed/36309755 http://dx.doi.org/10.1186/s40478-022-01461-1

Ejemplares similares

Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function
por: Teske, Nina C., et al.
Publicado: (2023)

Inhibition of DAMP signaling as an effective adjunctive treatment strategy in pneumococcal meningitis
por: Masouris, Ilias, et al.
Publicado: (2017)

Role of purinergic signaling in experimental pneumococcal meningitis
por: Zierhut, Marco, et al.
Publicado: (2017)

Pneumococcal meningitis: Clinical-pathological correlations (meningene-path)
por: Engelen-Lee, Joo-Yeon, et al.
Publicado: (2016)

Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study
por: Engelen-Lee, Joo-Yeon, et al.
Publicado: (2018)

SOP: emergency workup in patients with suspected acute bacterial meningitis
por: Dyckhoff-Shen, Susanne, et al.
Publicado: (2021)

Dramatic reduction of mortality in pneumococcal meningitis
por: Buchholz, Grete, et al.
Publicado: (2016)

Leukocyte Attraction by CCL20 and Its Receptor CCR6 in Humans and Mice with Pneumococcal Meningitis
por: Klein, Matthias, et al.
Publicado: (2014)

Histopathology of Listeria Meningitis
por: Engelen-Lee, Joo-Yeon, et al.
Publicado: (2018)

CCAAT/enhancer-binding protein δ (C/EBPδ) aggravates inflammation and bacterial dissemination during pneumococcal meningitis
por: Serón, Mercedes Valls, et al.
Publicado: (2015)

Reduced spiral ganglion neuronal loss by adjunctive neurotrophin-3 in experimental pneumococcal meningitis
por: Demel, Cornelia, et al.
Publicado: (2011)

Genetic Variation and Cerebrospinal Fluid Levels of Mannose Binding Lectin in Pneumococcal Meningitis Patients
por: Brouwer, Matthijs C., et al.
Publicado: (2013)

Infection of zebrafish embryos with live fluorescent Streptococcus pneumoniae as a real-time pneumococcal meningitis model
por: Jim, Kin Ki, et al.
Publicado: (2016)

Exome Array Analysis of Susceptibility to Pneumococcal Meningitis
por: Kloek, Anne T., et al.
Publicado: (2016)

Adjuvant glycerol is not beneficial in experimental pneumococcal meningitis
por: Blaser, Cornelia, et al.
Publicado: (2010)

Mast Cells Are Activated by Streptococcus pneumoniae In Vitro but Dispensable for the Host Defense Against Pneumococcal Central Nervous System Infection In Vivo
por: Fritscher, Johanna, et al.
Publicado: (2018)

Characterization of a Listeria monocytogenes meningitis mouse model
por: Koopmans, Merel M., et al.
Publicado: (2018)

Pneumococcal Meningitis in Adults: A Prospective Nationwide Cohort Study Over a 20-year Period
por: Koelman, Diederik L H, et al.
Publicado: (2021)

V-akt murine thymoma viral oncogene homolog 3 (AKT3) contributes to poor disease outcome in humans and mice with pneumococcal meningitis
por: Valls Serón, Mercedes, et al.
Publicado: (2016)

Targeting the complement system in bacterial meningitis
por: Koelman, Diederik L H, et al.
Publicado: (2019)

Inflammasome activation mediates inflammation and outcome in humans and mice with pneumococcal meningitis
por: Geldhoff, Madelijn, et al.
Publicado: (2013)

Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial
por: Kasanmoentalib, E. Soemirien, et al.
Publicado: (2015)

Sex‐based differences in the response to dexamethasone in bacterial meningitis: Analysis of the European dexamethasone in adulthood bacterial meningitis study
por: Dias, Sara P., et al.
Publicado: (2020)

What’s new in bacterial meningitis
por: Brouwer, Matthijs C., et al.
Publicado: (2016)

Variation of 46 Innate Immune Genes Evaluated for their Contribution in Pneumococcal Meningitis Susceptibility and Outcome
por: Ferwerda, Bart, et al.
Publicado: (2016)

Host genetic variability and pneumococcal disease: a systematic review and meta-analysis
por: Kloek, Anne T., et al.
Publicado: (2019)

Adjunctive dexamethasone treatment in adults with listeria monocytogenes meningitis: a prospective nationwide cohort study
por: Brouwer, Matthijs C., et al.
Publicado: (2023)

Apoptosis Is Essential for Neutrophil Functional Shutdown and Determines Tissue Damage in Experimental Pneumococcal Meningitis
por: Koedel, Uwe, et al.
Publicado: (2009)

Arterial cerebrovascular complications in 94 adults with acute bacterial meningitis
por: Klein, Matthias, et al.
Publicado: (2011)

Cryptococcal meningitis complicating sarcoidosis
por: Leonhard, Sonja E., et al.
Publicado: (2016)

Bacterial meningitis complicated by cerebral venous thrombosis
por: Deliran, Shahrzad S, et al.
Publicado: (2020)

Daptomycin in experimental murine pneumococcal meningitis
por: Mook-Kanamori, Barry B, et al.
Publicado: (2009)

Characterization of a pneumococcal meningitis mouse model
por: Mook-Kanamori, Barry, et al.
Publicado: (2012)

Community‐acquired bacterial meningitis in patients of 80 years and older
por: van Soest, Thijs M., et al.
Publicado: (2022)

Recurrent Community-Acquired Bacterial Meningitis in Adults
por: ter Horst, Liora, et al.
Publicado: (2020)

Community-acquired Bacterial Meningitis in Adults With Cerebrospinal Fluid Leakage
por: ter Horst, Liora, et al.
Publicado: (2020)

Mannose-binding lectin-associated serine protease 2 (MASP-2) contributes to poor disease outcome in humans and mice with pneumococcal meningitis
por: Kasanmoentalib, E. Soemirien, et al.
Publicado: (2017)

Campylobacter Fetus Meningitis in Adults: Report of 2 Cases and Review of the Literature
por: van Samkar, Anusha, et al.
Publicado: (2016)

Changing Epidemiology of Bacterial Meningitis Since Introduction of Conjugate Vaccines: 3 Decades of National Meningitis Surveillance in The Netherlands
por: Koelman, Diederik L H, et al.
Publicado: (2020)

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion
por: Iovino, Federico, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_uk66vpb6g531a1vc4239jvcja8