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PKD1 deficiency induces Bronchiectasis in a porcine ADPKD model

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a prevalent genetic disorder, mainly characterized by the development of renal cysts, as well as various extrarenal manifestations. Previous studies have shown that ADPKD is related to bronchiectasis, while its pathogenic mechanism...

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Detalles Bibliográficos
Autores principales: Wang, Runming, Li, Wenya, Dai, Haiting, Zhu, Mingli, Li, Lingyu, Si, Guohui, Bai, Yilina, Wu, Hanyu, Hu, Xiaoxiang, Xing, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617414/
https://www.ncbi.nlm.nih.gov/pubmed/36309681
http://dx.doi.org/10.1186/s12931-022-02214-3