Erythropoietin-PLGA-PEG as a local treatment to promote functional recovery and neurovascular regeneration after peripheral nerve injury

BACKGROUND: Traumatic peripheral nerve injury (TPNI) is a major medical problem with no universally accepted pharmacologic treatment. We hypothesized that encapsulation of pro-angiogenic erythropoietin (EPO) in amphiphilic PLGA-PEG block copolymers could serve as a local controlled-release drug deli...

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Detalles Bibliográficos
Autores principales: Manto, Kristen M., Govindappa, Prem Kumar, Martinazzi, Brandon, Han, Aijie, Hegarty, John P., Koroneos, Zachary, Talukder, M. A. Hassan, Elfar, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617443/
https://www.ncbi.nlm.nih.gov/pubmed/36307805
http://dx.doi.org/10.1186/s12951-022-01666-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617443/
https://www.ncbi.nlm.nih.gov/pubmed/36307805
http://dx.doi.org/10.1186/s12951-022-01666-5

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