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Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS

In mammalian cell nuclei, the nuclear lamina (NL) underlies the nuclear envelope (NE) to maintain nuclear structure. The nuclear lamins, the major structural components of the NL, are involved in the protection against NE rupture induced by mechanical stress. However, the specific role of the lamins...

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Detalles Bibliográficos
Autores principales: Kono, Yohei, Adam, Stephen A., Sato, Yuko, Reddy, Karen L., Zheng, Yixian, Medalia, Ohad, Goldman, Robert D., Kimura, Hiroshi, Shimi, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617480/
https://www.ncbi.nlm.nih.gov/pubmed/36301259
http://dx.doi.org/10.1083/jcb.202201024