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Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS
In mammalian cell nuclei, the nuclear lamina (NL) underlies the nuclear envelope (NE) to maintain nuclear structure. The nuclear lamins, the major structural components of the NL, are involved in the protection against NE rupture induced by mechanical stress. However, the specific role of the lamins...
Autores principales: | Kono, Yohei, Adam, Stephen A., Sato, Yuko, Reddy, Karen L., Zheng, Yixian, Medalia, Ohad, Goldman, Robert D., Kimura, Hiroshi, Shimi, Takeshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617480/ https://www.ncbi.nlm.nih.gov/pubmed/36301259 http://dx.doi.org/10.1083/jcb.202201024 |
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