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Microfluidic space coding for multiplexed nucleic acid detection via CRISPR-Cas12a and recombinase polymerase amplification

Fast, inexpensive, and multiplexed detection of multiple nucleic acids is of great importance to human health, yet it still represents a significant challenge. Herein, we propose a nucleic acid testing platform, named MiCaR, which couples a microfluidic device with CRISPR-Cas12a and multiplex recomb...

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Detalles Bibliográficos
Autores principales: Xu, Zhichen, Chen, Dongjuan, Li, Tao, Yan, Jiayu, Zhu, Jiang, He, Ting, Hu, Rui, Li, Ying, Yang, Yunhuang, Liu, Maili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617605/
https://www.ncbi.nlm.nih.gov/pubmed/36309521
http://dx.doi.org/10.1038/s41467-022-34086-y