HDAC6 Inhibition Reverses Cisplatin-Induced Mechanical Hypersensitivity via Tonic Delta Opioid Receptor Signaling

Peripheral neuropathic pain induced by the chemotherapeutic cisplatin can persist for months to years after treatment. Histone deacetylase 6 (HDAC6) inhibitors have therapeutic potential for cisplatin-induced neuropathic pain since they persistently reverse mechanical hypersensitivity and spontaneou...

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Detalles Bibliográficos
Autores principales: Zhang, Jixiang, Junigan, Jazzmine M., Trinh, Ronnie, Kavelaars, Annemieke, Heijnen, Cobi J., Grace, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617617/
https://www.ncbi.nlm.nih.gov/pubmed/36096670
http://dx.doi.org/10.1523/JNEUROSCI.1182-22.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617617/
https://www.ncbi.nlm.nih.gov/pubmed/36096670
http://dx.doi.org/10.1523/JNEUROSCI.1182-22.2022

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