The histone deacetylase SIRT6 promotes glycolysis through the HIF-1α/HK2 signaling axis and induces erlotinib resistance in non-small cell lung cancer

Erlotinib is a first-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). Overcoming erlotinib resistance is crucial to improve the survival of advanced non-small cell lung cancer (NSCLC) patients with sensitive EGFR mutations. It is also an important clinical problem th...

Descripción completa

Detalles Bibliográficos
Autores principales: You, Qiai, Wang, Jianmin, Yu, Yongxin, Li, Feng, Meng, Lingxin, Chen, Mingjing, Yang, Qiao, Xu, Zihan, Sun, Jianguo, Zhuo, Wenlei, Chen, Zhengtang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617843/
https://www.ncbi.nlm.nih.gov/pubmed/35915188
http://dx.doi.org/10.1007/s10495-022-01751-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617843/
https://www.ncbi.nlm.nih.gov/pubmed/35915188
http://dx.doi.org/10.1007/s10495-022-01751-y

Ejemplares similares