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The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors

Metastatic prostate cancer remains a major clinical challenge and metastatic lesions are highly heterogeneous and difficult to biopsy. Liquid biopsy provides opportunities to gain insights into the underlying biology. Here, using the highly sensitive enrichment-based sequencing technology, we provid...

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Detalles Bibliográficos
Autores principales: Chen, Sujun, Petricca, Jessica, Ye, Wenbin, Guan, Jiansheng, Zeng, Yong, Cheng, Nicholas, Gong, Linsey, Shen, Shu Yi, Hua, Junjie T., Crumbaker, Megan, Fraser, Michael, Liu, Stanley, Bratman, Scott V., van der Kwast, Theodorus, Pugh, Trevor, Joshua, Anthony M., De Carvalho, Daniel D., Chi, Kim N., Awadalla, Philip, Ji, Guoli, Feng, Felix, Wyatt, Alexander W., He, Housheng Hansen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617856/
https://www.ncbi.nlm.nih.gov/pubmed/36309516
http://dx.doi.org/10.1038/s41467-022-34012-2