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The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors
Metastatic prostate cancer remains a major clinical challenge and metastatic lesions are highly heterogeneous and difficult to biopsy. Liquid biopsy provides opportunities to gain insights into the underlying biology. Here, using the highly sensitive enrichment-based sequencing technology, we provid...
Autores principales: | Chen, Sujun, Petricca, Jessica, Ye, Wenbin, Guan, Jiansheng, Zeng, Yong, Cheng, Nicholas, Gong, Linsey, Shen, Shu Yi, Hua, Junjie T., Crumbaker, Megan, Fraser, Michael, Liu, Stanley, Bratman, Scott V., van der Kwast, Theodorus, Pugh, Trevor, Joshua, Anthony M., De Carvalho, Daniel D., Chi, Kim N., Awadalla, Philip, Ji, Guoli, Feng, Felix, Wyatt, Alexander W., He, Housheng Hansen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617856/ https://www.ncbi.nlm.nih.gov/pubmed/36309516 http://dx.doi.org/10.1038/s41467-022-34012-2 |
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