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Inhibition of CD40-TRAF6-dependent inflammatory activity halts the onset of diabetic retinopathy in streptozotocin-diabetic mice

Diabetes initiates inflammation that can impair the retinal vasculature, and lead to diabetic retinopathy; one of the leading causes of blindness. Inflammatory pathways have been examined as potential therapeutic targets for diabetic retinopathy, but there is still a need for early-stage treatments....

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Detalles Bibliográficos
Autores principales: Howell, Scott J., Lee, Chieh A., Zapadka, Thomas E., Lindstrom, Sarah I., Taylor, Brooklyn E., Taylor, Zakary R. R., Barber, Katherine G., Taylor, Patricia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617859/
https://www.ncbi.nlm.nih.gov/pubmed/36309487
http://dx.doi.org/10.1038/s41387-022-00225-z