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GPX4-independent ferroptosis—a new strategy in disease’s therapy

Ferroptosis is a form of programmed cell death characterized by intracellular iron accumulation and lipid peroxidation, and earlier studies identified glutathione peroxidase 4 (GPX4) as an essential regulator of this process. Ferroptosis plays an essential role in tumors, degenerative diseases, and...

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Detalles Bibliográficos
Autores principales: Ma, Tianyu, Du, Jingtong, Zhang, Yufeng, Wang, Yuyao, Wang, Bingxuan, Zhang, Tianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617873/
https://www.ncbi.nlm.nih.gov/pubmed/36309489
http://dx.doi.org/10.1038/s41420-022-01212-0