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Desmoglein-2 is important for islet function and β-cell survival

Type 1 diabetes is a complex disease characterized by the lack of endogenous insulin secreted from the pancreatic β-cells. Although β-cell targeted autoimmune processes and β-cell dysfunction are known to occur in type 1 diabetes, a complete understanding of the cell-to-cell interactions that suppor...

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Detalles Bibliográficos
Autores principales: Myo Min, Kay K., Rojas-Canales, Darling, Penko, Daniella, DeNichilo, Mark, Cockshell, Michaelia P., Ffrench, Charlie B., Thompson, Emma J., Asplund, Olof, Drogemuller, Christopher J., Prasad, Rashmi B., Groop, Leif, Grey, Shane T., Thomas, Helen E., Loudovaris, Thomas, Kay, Thomas W., Mahoney, My G., Jessup, Claire F., Coates, P. Toby, Bonder, Claudine S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617887/
https://www.ncbi.nlm.nih.gov/pubmed/36309486
http://dx.doi.org/10.1038/s41419-022-05326-2