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Polygenic heterogeneity in antidepressant treatment and placebo response

The genetic architecture of antidepressant response is poorly understood. Polygenic risk scores (PRS), exploration of placebo response and the use of sub-scales might provide insights. Here, we investigate the association between PRSs for relevant complex traits and response to vortioxetine treatmen...

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Detalles Bibliográficos
Autores principales: Nøhr, Anne Krogh, Forsingdal, Annika, Moltke, Ida, Howes, Oliver D., Vitezic, Morana, Albrechtsen, Anders, Dalby, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617908/
https://www.ncbi.nlm.nih.gov/pubmed/36309483
http://dx.doi.org/10.1038/s41398-022-02221-4