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Differential trafficking of ligands trogocytosed via CD28 versus CTLA4 promotes collective cellular control of co-stimulation

Intercellular communication is crucial for collective regulation of cellular behaviors. While clustering T cells have been shown to mutually control the production of key communication signals, it is unclear whether they also jointly regulate their availability and degradation. Here we use newly dev...

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Detalles Bibliográficos
Autores principales: Zenke, Simon, Sica, Mauricio P., Steinberg, Florian, Braun, Julia, Zink, Alicia, Gavrilov, Alina, Hilger, Alexander, Arra, Aditya, Brunner-Weinzierl, Monika, Elling, Roland, Beyersdorf, Niklas, Lämmermann, Tim, Smulski, Cristian R., Rohr, Jan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617924/
https://www.ncbi.nlm.nih.gov/pubmed/36309492
http://dx.doi.org/10.1038/s41467-022-34156-1