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Bromodomain-containing protein 4 (BRD4) as an epigenetic regulator of fatty acid metabolism genes and ferroptosis

Reprogramming lipid metabolism is considered a fundamental step in tumourigenesis that influences ferroptosis. However, molecular mechanisms between lipid metabolism and ferroptosis remain largely unknown. Results from the drug screening of 464 inhibitors (for 164 targets) applied to ferroptosis cel...

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Detalles Bibliográficos
Autores principales: Yang, Minghua, Liu, Ke, Chen, Pan, Zhu, Hongyi, Wang, Junjie, Huang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9617950/
https://www.ncbi.nlm.nih.gov/pubmed/36309482
http://dx.doi.org/10.1038/s41419-022-05344-0