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Regulated Restructuring of Mucins During Secretory Granule Maturation In Vivo
Mucins are large, highly glycosylated transmembrane and secreted proteins that line and protect epithelial surfaces. However, the details of mucin biosynthesis and packaging in vivo are largely unknown. Here, we demonstrate that multiple distinct mucins undergo intragranular restructuring during sec...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618048/ https://www.ncbi.nlm.nih.gov/pubmed/36252017 http://dx.doi.org/10.1073/pnas.2209750119 |