Regulated Restructuring of Mucins During Secretory Granule Maturation In Vivo

Mucins are large, highly glycosylated transmembrane and secreted proteins that line and protect epithelial surfaces. However, the details of mucin biosynthesis and packaging in vivo are largely unknown. Here, we demonstrate that multiple distinct mucins undergo intragranular restructuring during sec...

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Detalles Bibliográficos
Autores principales: Syed, Zulfeqhar A., Zhang, Liping, Tran, Duy T., Bleck, Christopher K. E., Ten Hagen, Kelly G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618048/
https://www.ncbi.nlm.nih.gov/pubmed/36252017
http://dx.doi.org/10.1073/pnas.2209750119

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