DNA polymerase epsilon binds histone H3.1-H4 and recruits MORC1 to mediate meiotic heterochromatin condensation

Heterochromatin is essential for genomic integrity and stability in eukaryotes. The mechanisms that regulate meiotic heterochromatin formation remain largely undefined. Here, we show that the catalytic subunit (POL2A) of Arabidopsis DNA polymerase epsilon (POL ε) is required for proper formation of...

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Detalles Bibliográficos
Autores principales: Wang, Cong, Huang, Jiyue, Li, Yingping, Zhang, Jun, He, Chengpeng, Li, Tianyang, Jiang, Danhua, Dong, Aiwu, Ma, Hong, Copenhaver, Gregory P., Wang, Yingxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618065/
https://www.ncbi.nlm.nih.gov/pubmed/36260743
http://dx.doi.org/10.1073/pnas.2213540119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618065/
https://www.ncbi.nlm.nih.gov/pubmed/36260743
http://dx.doi.org/10.1073/pnas.2213540119

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