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DNA polymerase epsilon binds histone H3.1-H4 and recruits MORC1 to mediate meiotic heterochromatin condensation
Heterochromatin is essential for genomic integrity and stability in eukaryotes. The mechanisms that regulate meiotic heterochromatin formation remain largely undefined. Here, we show that the catalytic subunit (POL2A) of Arabidopsis DNA polymerase epsilon (POL ε) is required for proper formation of...
Autores principales: | Wang, Cong, Huang, Jiyue, Li, Yingping, Zhang, Jun, He, Chengpeng, Li, Tianyang, Jiang, Danhua, Dong, Aiwu, Ma, Hong, Copenhaver, Gregory P., Wang, Yingxiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618065/ https://www.ncbi.nlm.nih.gov/pubmed/36260743 http://dx.doi.org/10.1073/pnas.2213540119 |
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