Cargando…
Prostaglandin production selectively in brain endothelial cells is both necessary and sufficient for eliciting fever
Fever is known to be elicited by prostaglandin E(2) acting on the brain, but its origin has remained disputed. We show in mice that selective deletion of prostaglandin synthesis in brain endothelial cells, but not in neural cells or myeloid cells, abolished fever induced by intravenous administratio...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618080/ https://www.ncbi.nlm.nih.gov/pubmed/36252026 http://dx.doi.org/10.1073/pnas.2122562119 |