The ulcerative colitis-associated gene FUT8 regulates the quantity and quality of secreted mucins

Mucins are the main macrocomponents of the mucus layer that protects the digestive tract from pathogens. Fucosylation of mucins increases mucus viscoelasticity and its resistance to shear stress. These properties are altered in patients with ulcerative colitis (UC), which is marked by a chronic infl...

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Detalles Bibliográficos
Autores principales: Cantero-Recasens, Gerard, Burballa, Carla, Ohkawa, Yuki, Fukuda, Tomohiko, Harada, Yoichiro, Curwin, Amy J., Brouwers, Nathalie, Thun, Gian A., Gu, Jianguo, Gut, Ivo, Taniguchi, Naoyuki, Malhotra, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618082/
https://www.ncbi.nlm.nih.gov/pubmed/36252012
http://dx.doi.org/10.1073/pnas.2205277119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618082/
https://www.ncbi.nlm.nih.gov/pubmed/36252012
http://dx.doi.org/10.1073/pnas.2205277119

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