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A generic framework for hierarchical de novo protein design

De novo protein design enables the exploration of novel sequences and structures absent from the natural protein universe. De novo design also stands as a stringent test for our understanding of the underlying physical principles of protein folding and may lead to the development of proteins with un...

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Detalles Bibliográficos
Autores principales: Harteveld, Zander, Bonet, Jaume, Rosset, Stéphane, Yang, Che, Sesterhenn, Fabian, Correia, Bruno E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618129/
https://www.ncbi.nlm.nih.gov/pubmed/36252041
http://dx.doi.org/10.1073/pnas.2206111119