Deterministic programming of human pluripotent stem cells into microglia facilitates studying their role in health and disease

Microglia, the resident immune cells of the central nervous system (CNS), are derived from yolk-sac macrophages that populate the developing CNS during early embryonic development. Once established, the microglia population is self-maintained throughout life by local proliferation. As a scalable sou...

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Detalles Bibliográficos
Autores principales: Speicher, Anna M., Korn, Lisanne, Csatári, Júlia, Gonzalez-Cano, Laura, Heming, Michael, Thomas, Christian, Schroeter, Christina B., Schafflick, David, Li, Xiaolin, Gola, Lukas, Engler, Alexander, Kaehne, Thilo, Vallier, Ludovic, Meuth, Sven G., Meyer zu Hörste, Gerd, Kovac, Stjepana, Wiendl, Heinz, Schöler, Hans R., Pawlowski, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618131/
https://www.ncbi.nlm.nih.gov/pubmed/36251998
http://dx.doi.org/10.1073/pnas.2123476119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618131/
https://www.ncbi.nlm.nih.gov/pubmed/36251998
http://dx.doi.org/10.1073/pnas.2123476119

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