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Nanoparticle-mediated selective Sfrp-1 silencing enhances bone density in osteoporotic mice

Osteoporosis (OP) is characterized by a loss in bone mass and mineral density. The stimulation of the canonical Wnt/β-catenin pathway has been reported to promote bone formation, this pathway is controlled by several regulators as secreted frizzled-related protein-1 (Sfrp-1), antagonist of the pathw...

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Detalles Bibliográficos
Autores principales: García-García, Patricia, Reyes, Ricardo, García-Sánchez, Daniel, Pérez-Campo, Flor María, Rodríguez-Rey, José Carlos, Évora, Carmen, Díaz-Rodríguez, Patricia, Delgado, Araceli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618188/
https://www.ncbi.nlm.nih.gov/pubmed/36309688
http://dx.doi.org/10.1186/s12951-022-01674-5