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Nanoparticle-mediated selective Sfrp-1 silencing enhances bone density in osteoporotic mice
Osteoporosis (OP) is characterized by a loss in bone mass and mineral density. The stimulation of the canonical Wnt/β-catenin pathway has been reported to promote bone formation, this pathway is controlled by several regulators as secreted frizzled-related protein-1 (Sfrp-1), antagonist of the pathw...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618188/ https://www.ncbi.nlm.nih.gov/pubmed/36309688 http://dx.doi.org/10.1186/s12951-022-01674-5 |