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Renal thrombotic microangiopathy and nephrotic proteinuria induced by intravitreal injection of aflibercept for diabetic macular edema

BACKGROUND: Vascular endothelial growth factor inhibitors (VEGFIs) are used to treat malignant neoplasms and ocular diseases by inhibiting angiogenesis. Systemic use of VEGFIs has various side effects, including hypertension, proteinuria, and thrombotic microangiopathy, but adverse events due to int...

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Detalles Bibliográficos
Autores principales: Kikuchi, Yawara, Odashima, Yoshimi, Yoshikawa, Kazuhiro, Oda, Tomoyasu, Tanaka, Fumitaka, Oikawa, Hiroki, Ishigaki, Yasushi, Asahi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618189/
https://www.ncbi.nlm.nih.gov/pubmed/36309669
http://dx.doi.org/10.1186/s12882-022-02986-2