An optimized exosome production strategy for enhanced yield while without sacrificing cargo loading efficiency

BACKGROUND: Exosome mediated mRNA delivery is a promising strategy for the treatment of multiple diseases. However, the low yield of exosomes is a bottleneck for clinical translation. In this study, we boosted exosome production via simultaneously reducing the expression of genes inhibiting exosome...

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Detalles Bibliográficos
Autores principales: Zhang, Rongxin, Bu, Te, Cao, Ruidan, Li, Zhelong, Wang, Chen, Huang, Bing, Wei, Mengying, Yuan, Lijun, Yang, Guodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618217/
https://www.ncbi.nlm.nih.gov/pubmed/36309712
http://dx.doi.org/10.1186/s12951-022-01668-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618217/
https://www.ncbi.nlm.nih.gov/pubmed/36309712
http://dx.doi.org/10.1186/s12951-022-01668-3

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