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B cells oppose Mycoplasma pneumoniae vaccine enhanced disease and limit bacterial colonization of the lungs

Development of an effective vaccine for Mycoplasma pneumoniae has been hindered by reports of Vaccine Enhanced Disease (VED) in test subjects vaccinated and challenged in studies conducted in the 1960s. The exact mechanism of disease exacerbation has yet to be fully described, but host immune respon...

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Detalles Bibliográficos
Autores principales: Gavitt, Tyler D., Mara, Arlind B., Goodridge, Meagan L., Ozyck, Rosemary Grace, Reinhardt, Emily, Miller, Jeremy M., Hunte, Morgan, Tulman, Edan R., Frasca Jr, Salvatore, Silbart, Lawrence K., Geary, Steven J., Szczepanek, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618410/
https://www.ncbi.nlm.nih.gov/pubmed/36310317
http://dx.doi.org/10.1038/s41541-022-00556-z