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B cells oppose Mycoplasma pneumoniae vaccine enhanced disease and limit bacterial colonization of the lungs
Development of an effective vaccine for Mycoplasma pneumoniae has been hindered by reports of Vaccine Enhanced Disease (VED) in test subjects vaccinated and challenged in studies conducted in the 1960s. The exact mechanism of disease exacerbation has yet to be fully described, but host immune respon...
Autores principales: | Gavitt, Tyler D., Mara, Arlind B., Goodridge, Meagan L., Ozyck, Rosemary Grace, Reinhardt, Emily, Miller, Jeremy M., Hunte, Morgan, Tulman, Edan R., Frasca Jr, Salvatore, Silbart, Lawrence K., Geary, Steven J., Szczepanek, Steven M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618410/ https://www.ncbi.nlm.nih.gov/pubmed/36310317 http://dx.doi.org/10.1038/s41541-022-00556-z |
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