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Topoisomerase 3b is dispensable for replication of a positive-sense RNA virus--murine coronavirus
A recent study demonstrated that a DNA-RNA dual-activity topoisomerase complex, TOP3B-TDRD3, is required for normal replication of positive-sense RNA viruses, including several human flaviviruses and coronaviruses; and the authors proposed that TOP3B is a target of antiviral drugs. Here we examined...
Autores principales: | Zhang, Tianyi, Su, Shuaikun, Altouma, Valerie, Zhu, Xingliang, Xue, Yutong, Shen, Weiping, Wilgenburg, Brian, Wang, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618458/ https://www.ncbi.nlm.nih.gov/pubmed/36328071 http://dx.doi.org/10.1016/j.antiviral.2022.105451 |
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