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Impact of NMDA receptor activation on DNA damage in PC12 neuron-like cell cultures in the presence of β-amyloid peptides
OBJECTIVE: This study aimed to investigate the effect of low nanomolar concentrations of Aβ1–40 and Aβ25–35 on DNA double-strand breaks following NMDA activation of cells. MATERIALS AND METHODS: After incubating the differentiated PC12 cells with Aβ(25−35), Aβ(1−40) or Aβ(1−42) for 24 h, the culture...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Netherlands
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618537/ https://www.ncbi.nlm.nih.gov/pubmed/36107376 http://dx.doi.org/10.1007/s11033-022-07856-6 |