Structure of the human heterodimeric transporter 4F2hc-LAT2 in complex with Anticalin, an alternative binding protein for applications in single-particle cryo-EM

Cryo-EM structure determination of relatively small and flexible membrane proteins at high resolution is challenging. Increasing the size and structural features by binding of high affinity proteins to the biomolecular target allows for better particle alignment and may result in structural models o...

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Detalles Bibliográficos
Autores principales: Jeckelmann, Jean-Marc, Lemmin, Thomas, Schlapschy, Martin, Skerra, Arne, Fotiadis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618567/
https://www.ncbi.nlm.nih.gov/pubmed/36310334
http://dx.doi.org/10.1038/s41598-022-23270-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618567/
https://www.ncbi.nlm.nih.gov/pubmed/36310334
http://dx.doi.org/10.1038/s41598-022-23270-1

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