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Structure of the human heterodimeric transporter 4F2hc-LAT2 in complex with Anticalin, an alternative binding protein for applications in single-particle cryo-EM
Cryo-EM structure determination of relatively small and flexible membrane proteins at high resolution is challenging. Increasing the size and structural features by binding of high affinity proteins to the biomolecular target allows for better particle alignment and may result in structural models o...
Autores principales: | Jeckelmann, Jean-Marc, Lemmin, Thomas, Schlapschy, Martin, Skerra, Arne, Fotiadis, Dimitrios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618567/ https://www.ncbi.nlm.nih.gov/pubmed/36310334 http://dx.doi.org/10.1038/s41598-022-23270-1 |
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