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The occurrence of ansamers in the synthesis of cyclic peptides

α-Amanitin is a bicyclic octapeptide composed of a macrolactam with a tryptathionine cross-link forming a handle. Previously, the occurrence of isomers of amanitin, termed atropisomers has been postulated. Although the total synthesis of α-amanitin has been accomplished this aspect still remains uns...

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Detalles Bibliográficos
Autores principales: Yao, Guiyang, Kosol, Simone, Wenz, Marius T., Irran, Elisabeth, Keller, Bettina G., Trapp, Oliver, Süssmuth, Roderich D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618573/
https://www.ncbi.nlm.nih.gov/pubmed/36310176
http://dx.doi.org/10.1038/s41467-022-34125-8