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Deep transfer learning of cancer drug responses by integrating bulk and single-cell RNA-seq data
Drug screening data from massive bulk gene expression databases can be analyzed to determine the optimal clinical application of cancer drugs. The growing amount of single-cell RNA sequencing (scRNA-seq) data also provides insights into improving therapeutic effectiveness by helping to study the het...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618578/ https://www.ncbi.nlm.nih.gov/pubmed/36310235 http://dx.doi.org/10.1038/s41467-022-34277-7 |