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CTGF as a multifunctional molecule for cartilage and a potential drug for osteoarthritis

CTGF is a multifunctional protein and plays different roles in different cells and under different conditions. Pamrevlumab, a monoclonal antibody against CTGF, is an FDA approved drug for idiopathic pulmonary fibrosis (IPF) and Duchenne muscular dystrophy (DMD). Recent studies have shown that CTGF a...

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Detalles Bibliográficos
Autores principales: Yang, Zihuan, Li, Weishi, Song, Chunli, Leng, Huijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618584/
https://www.ncbi.nlm.nih.gov/pubmed/36325449
http://dx.doi.org/10.3389/fendo.2022.1040526