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TCR repertoire profiling revealed antigen-driven CD8+ T cell clonal groups shared in synovial fluid of patients with spondyloarthritis

Spondyloarthritis (SpA) comprises a number of inflammatory rheumatic diseases with overlapping clinical manifestations. Strong association with several HLA-I alleles and T cell infiltration into an inflamed joint suggest involvement of T cells in SpA pathogenesis. In this study, we performed high-th...

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Detalles Bibliográficos
Autores principales: Komech, Ekaterina A., Koltakova, Anastasia D., Barinova, Anna A., Minervina, Anastasia A., Salnikova, Maria A., Shmidt, Evgeniya I., Korotaeva, Tatiana V., Loginova, Elena Y., Erdes, Shandor F., Bogdanova, Ekaterina A., Shugay, Mikhail, Lukyanov, Sergey, Lebedev, Yury B., Zvyagin, Ivan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618624/
https://www.ncbi.nlm.nih.gov/pubmed/36325356
http://dx.doi.org/10.3389/fimmu.2022.973243