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Urokinase-loaded cyclic RGD-decorated liposome targeted therapy for in-situ thrombus of pulmonary arteriole of pulmonary hypertension

Backgroud: In-situ thrombosis is a significant pathophysiological basis for the development of pulmonary hypertension (PH). However, thrombolytic therapy for in-situ thrombus in PH was often hampered by the apparent side effects and the low bioavailability of common thrombolytic medications. Nanosca...

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Detalles Bibliográficos
Autores principales: Li, Jingtao, Zhang, Xiaofeng, Mo, Yingying, Huang, Tongtong, Rao, Huaqing, Tan, Zhenyuan, Huang, Liuliu, Zeng, Decai, Jiang, Chunlan, Zhong, Yanfen, Cai, Yongzhi, Liang, Binbin, Wu, Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618629/
https://www.ncbi.nlm.nih.gov/pubmed/36324896
http://dx.doi.org/10.3389/fbioe.2022.1038829