Polyvalent guide RNAs for CRISPR antivirals

CRISPR effector Cas13 recognizes and degrades RNA molecules that are complementary to its guide RNA (gRNA) and possesses potential as an antiviral biotechnology because it can degrade viral mRNA and RNA genomes. Because multiplexed targeting is a critical strategy to improve viral suppression, we de...

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Detalles Bibliográficos
Autores principales: Bagchi, Rammyani, Tinker-Kulberg, Rachel, Salehin, Mohammad, Supakar, Tinku, Chamberlain, Sydney, Ligaba-Osena, Ayalew, Josephs, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618770/
https://www.ncbi.nlm.nih.gov/pubmed/36325075
http://dx.doi.org/10.1016/j.isci.2022.105333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618770/
https://www.ncbi.nlm.nih.gov/pubmed/36325075
http://dx.doi.org/10.1016/j.isci.2022.105333

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