Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells

The pancreatic hormone, glucagon, is known to regulate hepatic glucose production, but recent studies suggest that its regulation of hepatic amino metabolism is equally important. Here, we show that chronic glucagon receptor activation with a long-acting glucagon analog increases amino acid cataboli...

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Detalles Bibliográficos
Autores principales: Elmelund, Emilie, Galsgaard, Katrine D., Johansen, Christian D., Trammell, Samuel A.J., Bomholt, Anna B., Winther-Sørensen, Marie, Hunt, Jenna E., Sørensen, Charlotte M., Kruse, Thomas, Lau, Jesper F., Grevengoed, Trisha J., Holst, Jens J., Wewer Albrechtsen, Nicolai J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618771/
https://www.ncbi.nlm.nih.gov/pubmed/36325048
http://dx.doi.org/10.1016/j.isci.2022.105296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618771/
https://www.ncbi.nlm.nih.gov/pubmed/36325048
http://dx.doi.org/10.1016/j.isci.2022.105296

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