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Immune system disruptions implicated in whole blood epigenome-wide association study of depression among Parkinson's disease patients

Although Parkinson's Disease (PD) is typically described in terms of motor symptoms, depression is a common feature. We explored whether depression influences blood-based genome-wide DNA methylation (DNAm) in 692 subjects from a population-based PD case-control study, using both a history of cl...

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Detalles Bibliográficos
Autores principales: Paul, Kimberly C., Kusters, Cynthia, Furlong, Melissa, Zhang, Keren, Yu, Yu, Folle, Aline Duarte, Del Rosario, Irish, Keener, Adrienne, Bronstein, Jeff, Sinsheimer, Janet S., Horvath, Steve, Ritz, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618774/
https://www.ncbi.nlm.nih.gov/pubmed/36325427
http://dx.doi.org/10.1016/j.bbih.2022.100530