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Cancer cell intrinsic TIM-3 induces glioblastoma progression

Glioblastoma (GBM) is identified to share common signal pathways between glioma and immune cells. Here, we find that T cell immunoglobulin domain and mucin domain protein 3 (TIM-3) is one of the most common co-inhibitory immune checkpoints in GBM shared by tumor and non-tumor cells. Glioma cell-intr...

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Detalles Bibliográficos
Autores principales: Guo, Qing, Shen, Shuai, Guan, Gefei, Zhu, Chen, Zou, Cunyi, Cao, Jingyuan, Cheng, Wen, Xu, Xiaoyan, Yu, Juanhan, Lin, Zhiguo, Wang, Guoli, Chen, Ling, Cheng, Peng, Wu, Anhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618784/
https://www.ncbi.nlm.nih.gov/pubmed/36325060
http://dx.doi.org/10.1016/j.isci.2022.105329