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Metabolic fingerprinting of chemotherapy-resistant prostate cancer stem cells. An untargeted metabolomic approach by liquid chromatography-mass spectrometry

Chemoresistance is one of the most important challenges in cancer therapy. The presence of cancer stem cells within the tumor may contribute to chemotherapy resistance since these cells express high levels of extrusion pumps and xenobiotic metabolizing enzymes that inactivate the therapeutic drug. D...

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Detalles Bibliográficos
Autores principales: Bort, Alicia, G. Sánchez, Belén, León, Carlos, Nozal, Leonor, Mora-Rodríguez, José M., Castro, Florentina, Crego, Antonio L., Díaz-Laviada, Inés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618794/
https://www.ncbi.nlm.nih.gov/pubmed/36325358
http://dx.doi.org/10.3389/fcell.2022.1005675