Cargando…

β-Carboline dimers inhibit the tumor proliferation by the cell cycle arrest of sarcoma through intercalating to Cyclin-A2

β-Carbolines are potentially strong alkaloids with a wide range of bioactivities, and their dimers exhibit stronger antitumor activity other than the monomers. However, the detailed mechanisms of the β-carboline dimers in inhibiting sarcoma (SARC) remain unclear. The results showed that β-carboline-...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Huiya, Yu, Hongzhi, Li, Zhengyang, Cao, Zhi, Du, Youwei, Dai, Jiangkun, Zhi, Dongming, Xu, Yujie, Li, Na, Wang, Junru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618858/
https://www.ncbi.nlm.nih.gov/pubmed/36325324
http://dx.doi.org/10.3389/fimmu.2022.922183