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β-Carboline dimers inhibit the tumor proliferation by the cell cycle arrest of sarcoma through intercalating to Cyclin-A2
β-Carbolines are potentially strong alkaloids with a wide range of bioactivities, and their dimers exhibit stronger antitumor activity other than the monomers. However, the detailed mechanisms of the β-carboline dimers in inhibiting sarcoma (SARC) remain unclear. The results showed that β-carboline-...
Autores principales: | Ma, Huiya, Yu, Hongzhi, Li, Zhengyang, Cao, Zhi, Du, Youwei, Dai, Jiangkun, Zhi, Dongming, Xu, Yujie, Li, Na, Wang, Junru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618858/ https://www.ncbi.nlm.nih.gov/pubmed/36325324 http://dx.doi.org/10.3389/fimmu.2022.922183 |
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