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Sphingomyelin synthase 2 is a positive regulator of the CSF1R-STAT3 pathway in pancreatic cancer-associated macrophage

Background: Tumor-associated macrophages (TAMs) are one of the most abundant immune cells in the pancreatic cancer stroma and are related to the poor prognosis of pancreatic ductal adenocarcinoma (PDAC) patients. Therefore, targeting tumor-associated macrophages is a possible strategy for the treatm...

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Detalles Bibliográficos
Autores principales: He, Shuhua, Gu, Xiang, Yang, Jintong, Xu, Fei, Hu, Jiachun, Wang, Wei, Huang, Yiheng, Lou, Bin, Ding, Tingbo, Zhou, Lu, Ye, Deyong, Yu, Ker, Dong, Jibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618885/
https://www.ncbi.nlm.nih.gov/pubmed/36324684
http://dx.doi.org/10.3389/fphar.2022.902016