Cisapride induced hypoglycemia via the KCNH6 potassium channel

Mutations in KCNH6 has been proved to cause hypoinsulinemia and diabetes in human and mice. Cisapride is a stomach–intestinal motility drug used to treat gastrointestinal dysfunction. Cisapride has been reported to be a potential inhibitor of the KCNH family, but it remained unclear whether cisaprid...

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Detalles Bibliográficos
Autores principales: Lu, Jing, Shi, Ting-Ting, Yuan, Sha-Sha, Xie, Rong-Rong, Zhao, Ru-Xuan, Zhu, Juan-Juan, Yang, Jin-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618959/
https://www.ncbi.nlm.nih.gov/pubmed/36325440
http://dx.doi.org/10.3389/fendo.2022.1011238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618959/
https://www.ncbi.nlm.nih.gov/pubmed/36325440
http://dx.doi.org/10.3389/fendo.2022.1011238

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