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Cisapride induced hypoglycemia via the KCNH6 potassium channel
Mutations in KCNH6 has been proved to cause hypoinsulinemia and diabetes in human and mice. Cisapride is a stomach–intestinal motility drug used to treat gastrointestinal dysfunction. Cisapride has been reported to be a potential inhibitor of the KCNH family, but it remained unclear whether cisaprid...
Autores principales: | Lu, Jing, Shi, Ting-Ting, Yuan, Sha-Sha, Xie, Rong-Rong, Zhao, Ru-Xuan, Zhu, Juan-Juan, Yang, Jin-Kui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618959/ https://www.ncbi.nlm.nih.gov/pubmed/36325440 http://dx.doi.org/10.3389/fendo.2022.1011238 |
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