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Identification of active natural products that induce lysosomal biogenesis by lysosome-based screening and biological evaluation

Lysosomal biogenesis is an essential adaptive process by which lysosomes exert their function in maintaining cellular homeostasis. Defects in lysosomal enzymes and functions lead to lysosome-related diseases, including lysosomal storage diseases and neurodegenerative disorders. Thus, activation of t...

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Detalles Bibliográficos
Autores principales: Ding, Xiao, Yang, Xu, Zhao, Yueqin, Wang, Yinyuan, Fei, Jimin, Niu, Zhenpeng, Dong, Xianxiang, Wang, Xuenan, Liu, Biao, Li, Hongmei, Hao, Xiaojiang, Zhao, Yuhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9618995/
https://www.ncbi.nlm.nih.gov/pubmed/36325146
http://dx.doi.org/10.1016/j.heliyon.2022.e11179